Custom Synthesis

Shiva Pharmachem Pvt. Ltd. (SPPL) provides custom synthesis to support clients in development and manufacturing of API by providing Advanced Intermediates, specialty chemicals and fine chemicals as per customer requirement.

SPPL offers the following business models FTE, Fee for services, Fixed quotation for a project.

Custom synthesis activities on offer:

1. Synthesis from Gram to Kilogram quantities.
2. Process Development for existing molecules.
3. Pilot scale manufacturing
4. Contract Manufacturing.

SPPL offers a broad range of technologies to service its client needs at all stages of production.

The following is the list of reactions which we undertake at our Pilot Plant

1. Chlorination                    2. Bromination
3. Chiral synthesis              4. Friedel Craft Reactions
5. Chloro-sulfonation          6. Reduction
7. Cyclization                      8. Oxidation
9. Acylation                         10. Addition Reaction
11. Alkylation                     12.Functional Group Protection
13. Esterification                14. Metal Reduction
15 Diel-Alder Reaction        16. Mannic Reaction
17. Rearrangement.           18 Grignard Reaction

Factors which favors SPPL as custom synthesis partner

• Fully equipped state-of-art R&D and Q.C. laboratory.
• Highly skilled research teams headed by project leaders dedicated for individual projects.
• Faster product development with optimized cost. A highly efficient supply chain management and optimal utilization of capacities, coupled with strong R&D team enables us to pass on substantial cost benefits to our clients.
• SPPL is in a unique position to offer a single point of contact for R&D, process development and production outsourcing, which allows seamless flow of technology and production.
• The sound support of infrastructure and resource planning ensure that the company is financially self sufficient for project investments.